Sea Buckthorn Health Benefits

 

There are various research studies about sea buckthorn examining the anti-inflammatory, anticancer, antioxidant, and anti-atherosclerotic properties its leaves, roots, seeds, and berries.

While teas made from the seeds have laxative properties and help weight loss, infusions of the leaves have antidiarrheal properties; in addition, fruit teas strengthen the immune system, and show activity against skin diseases

 

Sea Buckthorn Health Benefits

Sea Buckthorn and Beautiful Facehttp://www.seabuckthorninsider.com/wp-content/uploads/2012/06/Sea-Buckthorn-for-Skin-Care1-300×300.jpg 300w, http://www.seabuckthorninsider.com/wp-content/uploads/2012/06/Sea-Buckthorn-for-Skin-Care1-50×50.jpg 50w, http://www.seabuckthorninsider.com/wp-content/uploads/2012/06/Sea-Buckthorn-for-Skin-Care1.jpg 342w” sizes=”(max-width: 300px) 100vw, 300px” style=”border-width: initial; border-style: none; margin: 4px 0px 12px 24px; padding: 0px; vertical-align: baseline; display: inline; float: right;”>In folk medicine and traditional use sea buckthorn is often considered a Panacea or cure-all. Need energy?  Eat some sea buckthorn berries. Skin issue?  Rub the sea buckthorn oils on your skin or face. Wound healing? Apply berry or seed oil and let it sit. Aging? Eat your daily miracle berries and watch the process slow. And so on. Sea buckthorn can be the answer to many, many health concerns.

It’s most well known, however, for promoting beauty, especially in the United States. Sea buckthorn has the rare Omega-7, a fatty acid that naturally occurs in the skin, and is the richest plant source known worldwide. Most information on this omega, and anecdotally from real world users, indicates that Omega-7 is fantastic for healthy, vibrant, and glowing hair, skin, and nails. Many personal care products have begun adding sea buckthorn to their formulas for this reason alone and many consumers supplementing with the oils are noticing these beauty effects on their own body.

Sea buckthorn really offers a laundry list of health benefits that are hard to encapsulate in one discussion. The nutritional profile is so robust that almost any issue one can imagine can be supported with sea buckthorn supplementation. For our purposes, we’ve tried to emphasize the most common uses and testimonials seen around.

 

Cardio   Skin Ailments GI / Digestive Weight Loss Cognitive
Liver   Beauty   Gynecological Immunity   Healing
Inflammation Vision Support Oral Health Sun Damage Animals
Chemotherapy Anti-Radiation Horses   Anti-Cancer

 

 

 

Both in vitro and human and animal in vivo studies on sea buckthorn have found a range of bioactive chemicals in its leaves, roots, seeds, and berries, known as seaberry, or Siberian pineapple, as well as the oil extracted from them; these compounds exhibit a wide range of anti-inflammatory, anticancer, antioxidant, and anti-atherosclerotic activities.

Table 1

The chemical composition of individual parts of the sea buckthorn (44; modified).

Part of sea buckthorn Chemical composition
Fruits (berries) Vitamins (C, E, B, K1, D, A, folic acid)
Macro and trace elements (potassium, magnesium, calcium, iron, sodium, manganese, zinc, copper, nickel)
Carotenoids
Phenolic compounds
Lipids
Amino acids
Organic acids
Proteins
Sugars
Pectins
Leaves Vitamins (E, folic acid)
Calcium, magnesium, potassium
Carotenoids
Phenolic compounds
Amino acids
Chlorophyll
Proteins
Pectins
Seeds Carotenoids
Phenolic compounds
Lipids
Proteins
Roots Carotenoids
Phenolic compounds
Lipids
Proteins
Bark Phenolic compounds

 

 

able 2

Sea buckthorn bioactive compounds and their therapeutic effects (44; modified).

Bioactive compound Therapeutic effect
Tocopherol Antioxidant
Analgesic action
Protection against degenerative changes, thrombosis, and muscle cramps
Carotenoids Antioxidant
Involved in the synthesis of collagen
Protection and restoration of the mucous membranes and epithelia
Enhancing the immune system
Phytosterols Anti-atherosclerotic action, anti-inflammatory and antibacterial properties
The prophylaxis and treatment of hypercholesterolemia-induced cardiovascular disorders by lowering serum cholesterol concentrations
Reducing the risk of stomach ulcers
Unsaturated fatty acids Protecting against cerebrovascular and cardiovascular disorders
Stimulating the immune system
Promoting cognitive function and bone health.
A positive effect on such neurological disorders as depression, schizophrenia, and Alzheimer’s disease
Organic acids Acceleration of wound healing
Protecting against cerebrovascular and cardiovascular disorders
Vitamin C Antioxidant
Involved in the synthesis of collagen
Maintaining correct cell membrane integrity
Vitamin K Prevention of bleeding
Reducing the risk of stomach ulcers
Assisting the reconstruction of skin damage
Phenolic compounds Antioxidant
Reducing the risk of cardiovascular disease
Involved in regulating heart rhythm
Prevention of tumors
Alleviating the symptoms of aging

 

 

 

Table 3

The effect of sea buckthorn on cancer cells in in vitro models.

Extract/chemical compound or other form obtained from sea buckthorn Cancer cells Concentration Effect Reference
EXTRACT OR OTHER FORM OBTAINED FROM SEA BUCKTHORN
Berry juice Cell lines of breast cancer, prostate, stomach, and a semi-colon 10–50 μl/ml of medium Inhibition of tumor cell proliferation of all tested lines Boivin et al., 2007
Extract from berries in different solvents Cancer cells of a semi-colon and liver <0.1–2% (v/v) of medium Inhibition of tumor cell proliferation of all tested lines; extract with ethyl acetate also caused apoptosis of these cells Grey et al., 2010
Ethanol-water extract from berries Cancer cells of the breast and a semi-colon 0.025–0.5% the dry weight in medium Inhibition of tumor cell proliferation of all tested lines Olsson et al., 2004
Ethanol-water extract from berries Acute myeloid leukemia cells 10–100 μg/ml Anti-proliferative action Zhamanbayeva et al., 2016
Ethanol extract from berries Acute myeloid leukemia cells 25, 50, and 100 μg/ml Anti-proliferative action Zhamanbaeva et al., 2014
Leaf extract C6 glioma cells 0.62, 6.2, and 62 μg/ml Anti-proliferative action Kim et al., 2017
Isorhamnetin isolated from berries of sea buckthorn Cancer cells of the liver 25–300 μg/ml of medium (IC50 = 75 μg/ml) Cytotoxicity against cancer cells-a decrease in their vitality, fragmentation and chromatin condensation Teng et al., 2006
Isorhamnetin isolated from berries of sea buckthorn Lung cancer cells 10–320 μg/ml Anti-proliferative action Li et al., 2015
Isorhamnetin isolated from berries of sea buckthorn Colorectal cancer cells 20 and 40 μM Anti-proliferative action Li et al., 2014
Procyanidins isolated from seeds Breast cancer cells 10–60 μg/ml Inducing apoptosis Wang et al., 2014

able 2

Sea buckthorn bioactive compounds and their therapeutic effects (44; modified).

Bioactive compound Therapeutic effect
Tocopherol Antioxidant
Analgesic action
Protection against degenerative changes, thrombosis, and muscle cramps
Carotenoids Antioxidant
Involved in the synthesis of collagen
Protection and restoration of the mucous membranes and epithelia
Enhancing the immune system
Phytosterols Anti-atherosclerotic action, anti-inflammatory and antibacterial properties
The prophylaxis and treatment of hypercholesterolemia-induced cardiovascular disorders by lowering serum cholesterol concentrations
Reducing the risk of stomach ulcers
Unsaturated fatty acids Protecting against cerebrovascular and cardiovascular disorders
Stimulating the immune system
Promoting cognitive function and bone health.
A positive effect on such neurological disorders as depression, schizophrenia, and Alzheimer’s disease
Organic acids Acceleration of wound healing
Protecting against cerebrovascular and cardiovascular disorders
Vitamin C Antioxidant
Involved in the synthesis of collagen
Maintaining correct cell membrane integrity
Vitamin K Prevention of bleeding
Reducing the risk of stomach ulcers
Assisting the reconstruction of skin damage
Phenolic compounds Antioxidant
Reducing the risk of cardiovascular disease
Involved in regulating heart rhythm
Prevention of tumors
Alleviating the symptoms of aging

 

 

 

Table 3

The effect of sea buckthorn on cancer cells in in vitro models.

Extract/chemical compound or other form obtained from sea buckthorn Cancer cells Concentration Effect Reference
EXTRACT OR OTHER FORM OBTAINED FROM SEA BUCKTHORN
Berry juice Cell lines of breast cancer, prostate, stomach, and a semi-colon 10–50 μl/ml of medium Inhibition of tumor cell proliferation of all tested lines Boivin et al., 2007
Extract from berries in different solvents Cancer cells of a semi-colon and liver <0.1–2% (v/v) of medium Inhibition of tumor cell proliferation of all tested lines; extract with ethyl acetate also caused apoptosis of these cells Grey et al., 2010
Ethanol-water extract from berries Cancer cells of the breast and a semi-colon 0.025–0.5% the dry weight in medium Inhibition of tumor cell proliferation of all tested lines Olsson et al., 2004
Ethanol-water extract from berries Acute myeloid leukemia cells 10–100 μg/ml Anti-proliferative action Zhamanbayeva et al., 2016
Ethanol extract from berries Acute myeloid leukemia cells 25, 50, and 100 μg/ml Anti-proliferative action Zhamanbaeva et al., 2014
Leaf extract C6 glioma cells 0.62, 6.2, and 62 μg/ml Anti-proliferative action Kim et al., 2017
Isorhamnetin isolated from berries of sea buckthorn Cancer cells of the liver 25–300 μg/ml of medium (IC50 = 75 μg/ml) Cytotoxicity against cancer cells-a decrease in their vitality, fragmentation and chromatin condensation Teng et al., 2006
Isorhamnetin isolated from berries of sea buckthorn Lung cancer cells 10–320 μg/ml Anti-proliferative action Li et al., 2015
Isorhamnetin isolated from berries of sea buckthorn Colorectal cancer cells 20 and 40 μM Anti-proliferative action Li et al., 2014
Procyanidins isolated from seeds Breast cancer cells 10–60 μg/ml Inducing apoptosis Wang et al., 2014

 

 

 

 

 

 

 

 

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